Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424178 | 0.84 | CNR1 (0.47) | CNR1CNR2PTGS2PTGS1 | |
| SCHEMBL8421921 | 0.83 | CA2 (0.44) | CNR1CNR2PTGS2PTGS1CA2 | |
| SCHEMBL8423893 | 0.82 | CNR1 (0.41) | CNR1CNR2PTGS2PTGS1CA2 | |
| SCHEMBL8424012 | 0.81 | PTGS1 (0.42) | CNR1CNR2PTGS2PTGS1CA2 | |
| SCHEMBL8423990 | 0.81 | CNR1 (0.40) | CNR1CNR2PTGS2PTGS1CA2 | |
| SCHEMBL8420759 | 0.81 | KDM4E (0.46) | KMT2ACNR1CNR2PTGS2PTGS1 | |
| SCHEMBL8421702 | 0.81 | PTGS1 (0.47) | CNR1CNR2PTGS2PTGS1 | |
| SCHEMBL8422208 | 0.81 | CNR1 (0.39) | CNR1CNR2PTGS2PTGS1CA2 | |
| SCHEMBL8123088 | 0.80 | PTGS2 (0.61) | CHRNA7PTGS2PTGS1CA2CA9 | |
| SCHEMBL8420775 | 0.79 | CNR1 (0.41) | CNR1CNR2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |