SCHEMBL8420820

SCHEMBL8420820

CC(C)(C)P(CC=Nc1ccccc1)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
GLA P06280 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8424296 0.81 KDM4E (0.32) ALDH1A1KDM4EGLAL3MBTL1MAPT
SCHEMBL17916180 0.74 ALDH1A1 (0.36) ALDH1A1KDM4EGLAL3MBTL1CYP2C9
SCHEMBL8422955 0.72 CYP2C9 (0.34) ALDH1A1KDM4EGLAL3MBTL1CYP2C9
SCHEMBL7516473 0.71 ALDH1A1 (0.45) ALDH1A1KDM4EGLAL3MBTL1CYP2C9
SCHEMBL10090559 0.71 ALDH1A1 (0.45) ALDH1A1KDM4EGLAL3MBTL1CYP2C9
SCHEMBL1116030 0.70 ALDH1A1 (0.44) ALDH1A1KDM4EGLAL3MBTL1CYP2C9
SCHEMBL10378413 0.70 ALDH1A1 (0.44) ALDH1A1KDM4EGLAL3MBTL1CYP2C9
SCHEMBL7120357 0.70 ALDH1A1 (0.44) ALDH1A1KDM4EGLAL3MBTL1CYP2C9
Hydrochloric Acid SCHEMBL2960053 0.69 ALDH1A1 (0.43) ALDH1A1KDM4EGLAL3MBTL1CYP2C9
Hydrochloric Acid SCHEMBL2960051 0.69 ALDH1A1 (0.43) ALDH1A1KDM4EGLAL3MBTL1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944638-A1 CIS-BRIDGED METAL COMPLEXES BASF AKTIENGESELLSCHAFT (DE) 1999-09-29 EP disclosed
WO-1998025939-A1 CIS-BRIDGED METAL COMPLEXES BASF AKTIENGESELLSCHAFT (DE) 1998-06-18 WO disclosed