SCHEMBL7516473

SCHEMBL7516473

C(CC=Nc1ccccc1)=Nc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
MAOA P21397 1/20 0.41
KDM4E B2RXH2 2/20 0.39
GLA P06280 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 5/20 0.38
CYP2C9 P11712 1/20 0.38
MAPT P10636 4/20 0.36
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
MEN1 O00255 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
USP2 O75604 1/20 0.36
GAA P10253 1/20 0.36
ALOX12 P18054 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10090559 1.00 ALDH1A1 (0.45) ALDH1A1MAOAKDM4EGLAL3MBTL1
Hydrochloric Acid SCHEMBL2960051 0.97 ALDH1A1 (0.43) ALDH1A1MAOAKDM4EGLAL3MBTL1
Hydrochloric Acid SCHEMBL2960053 0.97 ALDH1A1 (0.43) ALDH1A1MAOAKDM4EGLAL3MBTL1
SCHEMBL16187277 0.88 ALDH1A1 (0.37) ALDH1A1MAOAKDM4EGLAL3MBTL1
SCHEMBL19932533 0.85 ALDH1A1 (0.38) ALDH1A1MAOAKDM4EGLAL3MBTL1
SCHEMBL10122037 0.85 ALDH1A1 (0.38) ALDH1A1MAOAKDM4EGLAL3MBTL1
SCHEMBL3803095 0.85 ALDH1A1 (0.38) ALDH1A1MAOAKDM4EGLAL3MBTL1
SCHEMBL3803101 0.85 ALDH1A1 (0.38) ALDH1A1MAOAKDM4EGLAL3MBTL1
SCHEMBL15910559 0.85 ALDH1A1 (0.38) ALDH1A1MAOAKDM4EGLAL3MBTL1
SCHEMBL8494111 0.85 ALDH1A1 (0.38) ALDH1A1MAOAKDM4EGLAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624391-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2026-05-12 US disclosed
US-20240132948-A1 Cyanine Dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2024-04-25 US disclosed
US-11624089-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-04-11 US disclosed
US-11572475-B2 Carbocyanines for G-quadruplex DNA stabilization and telomerase inhibition GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-02-07 US disclosed
CN-114450814-A Laser element, compound, method for producing compound, and laser sensitizer 国立大学法人九州大学 2022-05-06 CN disclosed
CN-110352036-A Polymerizable near infrared dyes 普罗菲尤萨股份有限公司 2019-10-18 CN disclosed
EP-1196398-A4 BRIDGED FLUORESCENT DYES, THEIR PREPARATION AND THEIR USE IN ASSAYS SURROMED INC (US) 2002-11-06 EP disclosed
US-6403807-B1 CYANINE DYES HAVING SEPARATE SECOND LINKING CHAIN JOINING TWO HETEROCYCLES TO RESTRAIN COMPOUND INTO DESIRED CONFORMATION WHICH ABSORBS ELECTROMAGNETIC ENERGY AND EMITS FLUORESCENCE AT SPECIFIED WAVELENGTHS SURROMED, INC. 2002-06-11 US disclosed
WO-2002040698-A2 ANALYSIS OF SOLUBLE FACTOR BIOLOGICAL MARKERS SURROMED, INC. (US) 2002-05-23 WO disclosed
EP-1196398-A1 BRIDGED FLUORESCENT DYES, THEIR PREPARATION AND THEIR USE IN ASSAYS Surromed, Inc. (US) 2002-04-17 EP disclosed
WO-2001002374-A1 BRIDGED FLUORESCENT DYES, THEIR PREPARATION AND THEIR USE IN ASSAYS SURROMED, INC. (US) 2001-01-11 WO disclosed
EP-0552646-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1998-08-12 EP disclosed
US-5346810-A Oxonol dye which is decolored by development FUJI PHOTO FILM CO., LTD. (JP) 1994-09-13 US disclosed
EP-0552646-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-07-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132948-A1 Cyanine Dyes ABCG2, IK, ACR ALDH1A1 1447/4885MAOA 2397/4885KDM4E 2687/4885
US-11624089-B2 Cyanine dyes ABCG2, IK, ACR ALDH1A1 1447/4885MAOA 2397/4885KDM4E 2687/4885
US-11572475-B2 Carbocyanines for G-quadruplex DNA stabilization and telomerase inhibition POT1, TERT, TERF2 ALDH1A1 4075/4885MAOA 4643/4885KDM4E 2932/4885
US-12624391-B2 Cyanine dyes POLL, POLR2E, POLR2H ALDH1A1 3243/4885MAOA 1956/4885KDM4E 3684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.