Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 7/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419749 | 0.99 | EDNRA (0.44) | EDNRAMCL1BCL2A1SCN9AMEN1 | |
| SCHEMBL8421220 | 0.98 | EDNRA (0.45) | EDNRAMCL1BCL2A1SCN9AMEN1 | |
| SCHEMBL8419444 | 0.96 | EDNRA (0.43) | EDNRASCN9AMEN1KMT2ANPSR1 | |
| SCHEMBL8423236 | 0.86 | MEN1 (0.48) | SCN9AMEN1KMT2ANPSR1GPR55 | |
| SCHEMBL8419290 | 0.85 | CNR1 (0.48) | MCL1SCN9AMEN1KMT2ANPSR1 | |
| SCHEMBL8421502 | 0.85 | CNR1 (0.51) | SCN9AMEN1KMT2ANPSR1GPR55 | |
| SCHEMBL8423223 | 0.85 | PIK3CA (0.46) | SCN9AMEN1KMT2AL3MBTL1PIK3CA | |
| SCHEMBL8419910 | 0.84 | MCL1 (0.44) | MCL1BCL2A1SCN9AMEN1KMT2A | |
| SCHEMBL8420124 | 0.84 | ALDH1A1 (0.39) | MCL1BCL2A1SCN9AMEN1KMT2A | |
| SCHEMBL8421067 | 0.84 | SQOR (0.45) | SCN9AMEN1KMT2ANPSR1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916905-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIPYRETICS | G. D. SEARLE & CO. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5686470-A | 2, 3-substituted pyridines for the treatment of inflammation | WEIER RICHARD M (US) | 1997-11-11 | — | — | US | disclosed |