Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 10/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4119186 | 0.88 | CA12 (0.55) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL30172106 | 0.83 | PKM (0.56) | ALDH1A1L3MBTL1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL9353433 | 0.83 | L3MBTL1 (0.63) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL1249230 | 0.82 | MAPT (0.66) | MAPTL3MBTL1GAALMNAPOLB | |
| SCHEMBL27316975 | 0.81 | PARP10 (0.59) | ALDH1A1MAOB | |
| SCHEMBL10704889 | 0.81 | MAPT (0.44) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL9155792 | 0.81 | L3MBTL1 (0.61) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL4754075 | 0.81 | PLK1 (0.65) | MAPTALDH1A1HPGDRAB9AHTT | |
| SCHEMBL29241080 | 0.81 | MAOB (0.60) | MAOBMAOASMN1; SMN2 | |
| SCHEMBL17099938 | 0.80 | PARP10 (0.58) | ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947494-A1 | Derivatives of phenoxy acetic acid and phenoxymethyltetrazole having antitumor activity | F. HOFFMANN-LA ROCHE AG (CH) | 1999-10-06 | — | — | EP | disclosed |