Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.49 |
| ▸ | PPARD | Q03181 | 16/20 | 0.49 |
| ▸ | PPARG | P37231 | 11/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421612 | 0.91 | PPARA (0.44) | PPARAPPARDPPARG | |
| SCHEMBL9269577 | 0.85 | PPARG (0.38) | PPARAPPARDPPARG | |
| SCHEMBL8418577 | 0.82 | PPARA (0.41) | PPARAPPARD | |
| SCHEMBL8419836 | 0.79 | ALOX5 (0.41) | PPARAPPARD | |
| SCHEMBL8418495 | 0.79 | PPARA (0.37) | PPARAPPARD | |
| SCHEMBL8418491 | 0.79 | PPARA (0.39) | PPARAPPARD | |
| SCHEMBL8417976 | 0.79 | PPARA (0.42) | PPARAPPARD | |
| SCHEMBL8418566 | 0.78 | FDFT1 (0.45) | PPARA | |
| SCHEMBL27460108 | 0.78 | ALOX5 (0.36) | PPARAPPARDPPARG | |
| SCHEMBL8418498 | 0.78 | PTGS2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |