Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | USP8 | P40818 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423819 | 0.94 | PTGS2 (0.51) | PTGS2MMP2CYP2C9CA2CA1 | |
| SCHEMBL8424010 | 0.94 | PTGS2 (0.51) | PTGS2MMP2CYP2C9CA2CA1 | |
| SCHEMBL8422373 | 0.89 | CYP2C9 (0.55) | PTGS2MMP2CYP2C9CA2CA1 | |
| SCHEMBL8423874 | 0.88 | CYP2C9 (0.49) | PTGS2MMP2CYP2C9CA2CA1 | |
| SCHEMBL8420750 | 0.87 | CYP2C9 (0.63) | PTGS2CYP2C9CA2CA1MEN1 | |
| SCHEMBL8421778 | 0.87 | PTGS2 (0.56) | PTGS2CYP2C9MEN1MAPTKMT2A | |
| SCHEMBL8422146 | 0.87 | PTGS2 (0.56) | PTGS2MMP2CYP2C9CA2CA1 | |
| SCHEMBL8421860 | 0.87 | CYP2C9 (0.48) | PTGS2MMP2CYP2C9CA2CA1 | |
| SCHEMBL8423868 | 0.86 | CYP2C9 (0.53) | PTGS2MMP2CYP2C9CA2CA1 | |
| SCHEMBL8733829 | 0.85 | PTGS2 (0.54) | PTGS2MMP2CYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |