SCHEMBL8422162

SCHEMBL8422162

C=Cc1cc(C(C)(C)C)ccc1OCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.63
SMN1; SMN2 Q16637 3/20 0.53
PTGDR2 Q9Y5Y4 7/20 0.49
ELANE P08246 1/20 0.44
CD69 Q07108 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
POLB P06746 1/20 0.44
TSHR P16473 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PTGDR Q13258 1/20 0.44
FFAR1 O14842 1/20 0.43
NPSR1 Q6W5P4 2/20 0.43
PPARD Q03181 1/20 0.43
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642604 0.87 CYP2C19 (0.65) CYP2C19SMN1; SMN2PTGDR2ELANECD69
SCHEMBL13757719 0.82 CYP2C19 (0.74) CYP2C19SMN1; SMN2PTGDR2ELANECD69
SCHEMBL17896571 0.80 CYP2C19 (0.72) CYP2C19SMN1; SMN2PTGDR2ELANECD69
SCHEMBL5284414 0.79 PTGDR2 (0.70) CYP2C19SMN1; SMN2PTGDR2ELANECD69
SCHEMBL4380943 0.78 CYP2C19 (0.61) CYP2C19SMN1; SMN2PTGDR2ELANECD69
SCHEMBL13624055 0.78 CYP2C19 (0.68) CYP2C19SMN1; SMN2PTGDR2ELANECD69
SCHEMBL4642505 0.78 CYP2C19 (1.00) CYP2C19SMN1; SMN2PTGDR2ELANECD69
SCHEMBL5321878 0.78 CYP2C19 (0.68) CYP2C19SMN1; SMN2PTGDR2ELANECD69
SCHEMBL14076372 0.78 CYP2C19 (0.68) CYP2C19SMN1; SMN2PTGDR2ELANECD69
SCHEMBL4909292 0.78 CYP2C19 (0.68) CYP2C19SMN1; SMN2PTGDR2ELANECD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5976759-A ALKALI SOLUBLE BY HEATING WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-02 US disclosed