Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423851 | 0.91 | HTR1D (0.59) | HTR1DLMNAEDNRBEDNRASMN1; SMN2 | |
| SCHEMBL8425473 | 0.85 | HTR1D (0.52) | HTR1DLMNAEDNRBEDNRAMEN1 | |
| SCHEMBL8421954 | 0.85 | LMNA (0.48) | HTR1DLMNASMN1; SMN2SIGMAR1SCN9A | |
| SCHEMBL8422440 | 0.84 | SLC6A2 (0.41) | LMNAMEN1KMT2A | |
| SCHEMBL8425640 | 0.81 | TACR1 (0.41) | MEN1KMT2A | |
| SCHEMBL8423963 | 0.81 | LMNA (0.46) | HTR1DLMNAHTTSIGMAR1SCN9A | |
| SCHEMBL8425616 | 0.81 | HTR1D (0.45) | HTR1DLMNASMN1; SMN2HTTSIGMAR1 | |
| SCHEMBL8422132 | 0.80 | HTR1D (0.43) | HTR1DLMNAHTTSIGMAR1SCN9A | |
| SCHEMBL8425741 | 0.78 | NPSR1 (0.52) | HTR1DLMNAHTTSIGMAR1SCN9A | |
| SCHEMBL8422259 | 0.78 | HTR1D (0.43) | HTR1DLMNAHTTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919802-A | Methods of preventing and/or treating temporal lobe epilepsy | PRINCETON UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |