Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422440 | 0.89 | SLC6A2 (0.41) | ALDH1A1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL8422264 | 0.81 | HTR1D (0.57) | MEN1KMT2A | |
| SCHEMBL8424657 | 0.81 | OPRL1 (0.49) | ALDH1A1OPRL1OPRK1MEN1KMT2A | |
| SCHEMBL8520123 | 0.79 | MAPT (0.49) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL666867 | 0.78 | OPRL1 (0.61) | ALDH1A1OPRL1MEN1KMT2A | |
| SCHEMBL8423867 | 0.75 | OPRL1 (0.44) | OPRL1OPRK1OPRD1 | |
| SCHEMBL8425620 | 0.74 | DRD2 (0.41) | SLC6A2SLC6A4 | |
| SCHEMBL7038207 | 0.72 | HTR1D (0.69) | ALDH1A1OPRL1MEN1KMT2A | |
| SCHEMBL8425473 | 0.72 | HTR1D (0.52) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8423851 | 0.72 | HTR1D (0.59) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919802-A | Methods of preventing and/or treating temporal lobe epilepsy | PRINCETON UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |