Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423851 | 0.94 | HTR1D (0.59) | HTR1DMEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL8422264 | 0.85 | HTR1D (0.57) | HTR1DMEN1KMT2ASIGMAR1LMNA | |
| SCHEMBL8520123 | 0.83 | MAPT (0.49) | HTR1DMEN1KMT2AMAPTLMNA | |
| SCHEMBL8563172 | 0.80 | HTR1D (0.53) | HTR1DSIGMAR1LMNAGAAMAPK1 | |
| SCHEMBL8424340 | 0.76 | OPRL1 (0.51) | MEN1KMT2AMAPTSIGMAR1LMNA | |
| SCHEMBL8425616 | 0.76 | HTR1D (0.45) | HTR1DMAPTSIGMAR1LMNAGAA | |
| SCHEMBL7041675 | 0.74 | HTR1D (0.69) | HTR1D | |
| SCHEMBL8422440 | 0.74 | SLC6A2 (0.41) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8425640 | 0.72 | TACR1 (0.41) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11094660 | 0.72 | MAPT (0.54) | MEN1KMT2AMAPTSIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919802-A | Methods of preventing and/or treating temporal lobe epilepsy | PRINCETON UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |