Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CNR1 | P21554 | 10/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421921 | 0.84 | CA2 (0.44) | PTGS1PTGS2CA2CA12CA1 | |
| SCHEMBL8423893 | 0.83 | CNR1 (0.41) | PTGS1PTGS2CA2CA12CA1 | |
| SCHEMBL8689215 | 0.83 | PTGS2 (0.65) | PTGS1PTGS2CA2CA12CA1 | |
| SCHEMBL8424178 | 0.82 | CNR1 (0.47) | PTGS1PTGS2CNR1CNR2 | |
| SCHEMBL8423990 | 0.82 | CNR1 (0.40) | PTGS1PTGS2CA2CA12CA1 | |
| SCHEMBL8424012 | 0.82 | PTGS1 (0.42) | PTGS1PTGS2CA2CA12CA1 | |
| SCHEMBL8422208 | 0.81 | CNR1 (0.39) | PTGS1PTGS2CA2CA12CA1 | |
| SCHEMBL8422347 | 0.80 | PTGS1 (0.39) | PTGS1PTGS2CA2CA12CA1 | |
| SCHEMBL8421702 | 0.80 | PTGS1 (0.47) | PTGS1PTGS2CNR1CNR2F10 | |
| SCHEMBL8421862 | 0.80 | PTGS2 (0.44) | PTGS1PTGS2CNR1CNR2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |