Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | NAT1 | P18440 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423988 | 0.84 | PTGES (0.43) | PTGESALOX5NAT1KDM1ALMNA | |
| SCHEMBL8421920 | 0.84 | PTGES (0.44) | PTGESALOX5NAT1KDM1ALMNA | |
| SCHEMBL8421861 | 0.84 | PTGES (0.41) | PTGESALOX5NAT1KDM1ALMNA | |
| SCHEMBL8423891 | 0.82 | ALDH1A1 (0.43) | PTGESALOX5NAT1KDM1ALMNA | |
| SCHEMBL8424009 | 0.82 | PTGES (0.43) | PTGESALOX5NAT1KDM1ALMNA | |
| SCHEMBL8424177 | 0.82 | PTGES (0.43) | PTGESALOX5NAT1KDM1ALMNA | |
| SCHEMBL8422206 | 0.81 | PTGES (0.42) | PTGESALOX5NAT1KDM1ALMNA | |
| SCHEMBL8688432 | 0.81 | NAT1 (0.39) | PTGESALOX5NAT1KDM1ALMNA | |
| SCHEMBL8422280 | 0.79 | PTGES (0.41) | PTGESALOX5NAT1KDM1ALMNA | |
| SCHEMBL8421700 | 0.79 | PTGES (0.43) | PTGESALOX5KDM1ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |