Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420285 | 0.94 | SMN1; SMN2 (0.62) | SMN1; SMN2HTTGAACYP1A2CYP3A4 | |
| SCHEMBL8420219 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2HTTGAACYP1A2CYP3A4 | |
| SCHEMBL8422410 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTGAACYP1A2CYP3A4 | |
| SCHEMBL8420658 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTGAAALDH1A1RAB9A | |
| SCHEMBL8420292 | 0.80 | GAA (0.68) | SMN1; SMN2HTTGAACYP1A2CYP3A4 | |
| SCHEMBL8422575 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTGAAALDH1A1RAB9A | |
| SCHEMBL949371 | 0.76 | GAA (0.70) | SMN1; SMN2HTTGAAALDH1A1MAPT | |
| SCHEMBL8422566 | 0.76 | NR1H4 (0.59) | SMN1; SMN2HTTNR1H4 | |
| SCHEMBL17413764 | 0.74 | FFAR1 (0.57) | ALDH1A1 | |
| SCHEMBL17413766 | 0.73 | LTB4R (0.60) | CYP2C9HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |