Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420285 | 0.88 | SMN1; SMN2 (0.62) | SMN1; SMN2HTTMEN1KMT2ATSHR | |
| SCHEMBL8422404 | 0.87 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTMEN1KMT2ATSHR | |
| SCHEMBL8419001 | 0.83 | KDM4E (0.57) | SMN1; SMN2HTTMEN1KMT2APOLB | |
| SCHEMBL8422410 | 0.76 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTMEN1KMT2ATSHR | |
| SCHEMBL8420292 | 0.75 | GAA (0.68) | SMN1; SMN2HTTMEN1KMT2ARAB9A | |
| SCHEMBL9798378 | 0.74 | PPARD (0.59) | MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL949371 | 0.72 | GAA (0.70) | SMN1; SMN2HTTALDH1A1GAANR1H4 | |
| SCHEMBL8420287 | 0.72 | HTT (0.53) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL8422575 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTMEN1KMT2ARAB9A | |
| SCHEMBL8422566 | 0.72 | NR1H4 (0.59) | SMN1; SMN2HTTNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |