Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | EYA2 | O00167 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421647 | 0.92 | CA2 (0.56) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL2807141 | 0.85 | TDP1 (0.56) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL12243695 | 0.81 | TDP1 (0.56) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL2284795 | 0.81 | TDP1 (0.56) | TDP1EYA2APPACEKDM4E | |
| Edetic Acid SCHEMBL17984124 | 0.80 | TDP1 (0.61) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL8423257 | 0.80 | OPRK1 (0.54) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7564337 | 0.79 | TDP1 (0.58) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL9878685 | 0.79 | TDP1 (0.52) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL19177822 | 0.79 | TDP1 (0.52) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL2441712 | 0.79 | MEP1B (0.49) | TDP1EYA2APPACEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668854-B1 | USE OF N-ARYLMETHYLENE, ETHYLENEDIAMINETRIACETATES N-ARYLMETHYLENE IMINODIACETATES OR N,N'-DIARYLMETHYLENE ETHYLENEDIAMINACETATES FOR USE IN COMBATTING OXIDATIVE STRESS | OREAL (FR) | 1999-10-13 | — | — | EP | claimed |
| US-5629436-A | Use of N-arylmethylene ethylenediaminetriacetates N-arylmethylene iminodiacetates or N,N'-diarylmethylene ethylenediamineacetates against oxidative stress | L'OREAL (FR) | 1997-05-13 | — | — | US | claimed |