SCHEMBL8423231

SCHEMBL8423231

O=C1C=C(OC(=O)c2cc(F)c3c(c2Cl)C(OCCF)CCS3(=O)=O)CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8400554 0.81 KEAP1 (0.31)
SCHEMBL8400572 0.80 L3MBTL1 (0.32)
SCHEMBL8427307 0.78
SCHEMBL9004057 0.72
SCHEMBL8423663 0.70
SCHEMBL7853482 0.64
SCHEMBL8351362 0.64
SCHEMBL8402382 0.62
SCHEMBL8405172 0.61 GAA (0.32)
SCHEMBL9298583 0.58 KMT2A (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981439-A APPLYING TO WEEDS OR TO SOIL AN EFFECTIVE HERBICIDAL AMOUNT OF A CYCLOHEXANEDIONE DERIVATIVES IDEMITSU KOSAN CO., LTD. (JP) 1999-11-09 US disclosed
EP-0949257-A1 CYCLOHEXANEDIONE DERIVATIVES AND HERBICIDES PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1999-10-13 EP disclosed
US-5801121-A Cyclohexanedione derivatives and herbicide containing them IDEMITSU KOSAN CO., LTD. (JP) 1998-09-01 US disclosed