Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404136 | 0.83 | GAA (0.36) | GAAADRB2TSHRPOLBMAPT | |
| SCHEMBL8400572 | 0.80 | L3MBTL1 (0.32) | GAATSHRPOLBMAPK1ALDH1A1 | |
| SCHEMBL8072009 | 0.76 | ALDH1A1 (0.35) | GAATSHRPOLBMAPTHIF1A | |
| SCHEMBL8405173 | 0.75 | KDM4E (0.32) | GAATSHRPOLBMAPTHIF1A | |
| SCHEMBL8405207 | 0.70 | KDM4E (0.38) | GAATSHRMAPTALDH1A1CYP4F2 | |
| SCHEMBL8400559 | 0.70 | — | — | |
| SCHEMBL4501337 | 0.65 | TSHR (0.46) | TSHRMAPTMAPK1ALDH1A1CYP4F2 | |
| SCHEMBL6721445 | 0.65 | CYP4F2 (0.38) | GAATSHRPOLBMAPTHIF1A | |
| SCHEMBL8400554 | 0.65 | KEAP1 (0.31) | — | |
| SCHEMBL9873755 | 0.64 | MTOR (0.42) | GAATSHRPOLBMAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863866-A | HERBICIDES TO KILL WEEDS BUT NOT CROPS | IDEMITSU KOSAN CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0819691-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-01-21 | — | — | EP | disclosed |