Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494260 | 0.81 | GRM2 (0.43) | ALOX5DRD2DRD3KCNH2GRM2 | |
| SCHEMBL8425507 | 0.76 | NOTUM (0.43) | DRD2DRD3KCNH2 | |
| SCHEMBL10804834 | 0.75 | POLB (0.44) | TP53KMT2AGAAALDH1A1MAPT | |
| SCHEMBL8424267 | 0.72 | ALOX5 (0.39) | ALOX5TP53GRM2FADS1MEN1 | |
| SCHEMBL10803755 | 0.72 | KMT2A (0.37) | TP53KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9482008 | 0.72 | ALDH1A1 (0.49) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL9482012 | 0.72 | ALDH1A1 (0.49) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL8428110 | 0.71 | ALOX5 (0.39) | ALOX5TP53DRD2DRD3KCNH2 | |
| SCHEMBL8427942 | 0.69 | ALOX5 (0.40) | ALOX5TP53DRD2DRD3KCNH2 | |
| SCHEMBL10983305 | 0.68 | DRD2 (0.49) | ALOX5DRD2DRD3KCNH2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636616-B1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-10-27 | — | — | EP | disclosed |
| US-5484933-A | Process for production of fluoroalkane carboxamide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0636616-A1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-01 | — | — | EP | disclosed |