SCHEMBL8423637

SCHEMBL8423637

C=C(CC=C(C)C(=O)O)C(=O)OCCO.C=C(CCCCC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
MGLL Q99685 1/20 0.36
FNTA P49354 2/20 0.34
FNTB P49356 2/20 0.34
THRB P10828 1/20 0.34
PGGT1B P53609 1/20 0.34
CNR2 P34972 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
ACHE P22303 1/20 0.33
DGKA P23743 1/20 0.33
PAM P19021 2/20 0.31
FAAH O00519 2/20 0.30
AKR1B1 P15121 1/20 0.30
EPHX2 P34913 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10482342 0.89 TSHR (0.52) TSHRMGLLFNTAFNTBTHRB
SCHEMBL1161024 0.87 TSHR (0.36) TSHRTHRB
SCHEMBL11236476 0.86 TSHR (0.58) TSHRMGLLTHRBACHEFAAH
SCHEMBL8636772 0.86 TSHR (0.50) TSHRMGLLTHRBACHEHCAR2
SCHEMBL7253549 0.86 TSHR (0.50) TSHRMGLLTHRBACHEHCAR2
SCHEMBL8961812 0.84 TSHR (0.57) TSHRFAAHHCAR2
SCHEMBL5898904 0.84 TSHR (0.57) TSHRFAAHHCAR2
SCHEMBL28707544 0.84 TSHR (0.57) TSHRFAAHHCAR2
SCHEMBL8438580 0.84 TSHR (0.57) TSHRFAAHHCAR2
SCHEMBL3670738 0.84 TSHR (0.47) TSHRTHRBFAAHHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0518225-B2 Aqueous pigmented inks for ink jet printers DU PONT (US) 1999-10-20 EP disclosed
US-5946012-A Reliable high performance drop generator for an inkjet printhead HEWLETT-PACKARD CO. (US) 1999-08-31 US disclosed
US-5874974-A Reliable high performance drop generator for an inkjet printhead HEWLETT-PACKARD COMPANY (US) 1999-02-23 US disclosed
EP-0633914-B1 An aqueous ink composition DU PONT (US) 1998-10-21 EP disclosed
EP-0565709-B1 AQUEOUS INK JET INKS CONTAINING POLYOL/ALKYLENE OXIDE CONDENSATES AS COSOLVENTS DU PONT (US) 1996-11-13 EP disclosed
EP-0509109-B1 Aqueous pigmented inks for ink jet printers DU PONT (US) 1995-07-12 EP disclosed
EP-0633914-A1 PENETRANTS FOR AQUEOUS INK JET INKS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-01-18 EP disclosed
EP-0565709-A1 AQUEOUS INK JET INKS CONTAINING POLYOL/ALKYLENE OXIDE CONDENSATES AS COSOLVENTS. DU PONT (US) 1993-10-20 EP disclosed
US-5221334-A Particles dispersed in a block copolymer linked to the pigment E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-22 US disclosed
WO-1993009194-A1 AQUEOUS INK JET INKS CONTAINING POLYOL/ALKYLENE OXIDE CONDENSATES AS COSOLVENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-13 WO disclosed
US-5205861-A Storage stability, image print quality E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-04-27 US disclosed
US-5180425-A Aqueous ink jet inks containing polyol/alkylene oxide condensates as cosolvents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-19 US disclosed
WO-1992022614-A1 PENETRANTS FOR AQUEOUS INK JET INKS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-23 WO disclosed
EP-0518225-A1 Aqueous pigmented inks for ink jet printers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-16 EP disclosed
US-5169438-A Storage stability, quick-drying E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-08 US disclosed
US-5160372-A Rapid drying; excellent decap performance; storage stable; good print quality images E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-03 US disclosed
EP-0509109-A1 Aqueous pigmented inks for ink jet printers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-21 EP disclosed
US-5141556-A Branched diols or hexene-1,2-diols along with a pigment or dye; rapid drying; storage stability; quality; thermal printers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-25 US disclosed
US-5085698-A Aqueous pigmented inks for ink jet printers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-02-04 US disclosed