Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423724 | 0.82 | SMN1; SMN2 (0.39) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8422259 | 0.82 | HTR1D (0.43) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8422132 | 0.82 | HTR1D (0.43) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8422448 | 0.82 | HTR1D (0.43) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8425741 | 0.82 | NPSR1 (0.52) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8423963 | 0.81 | LMNA (0.46) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8423536 | 0.79 | LMNA (0.47) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8425744 | 0.79 | GAA (0.44) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8425616 | 0.78 | HTR1D (0.45) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8422264 | 0.78 | HTR1D (0.57) | HTR1DHTTLMNASMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919802-A | Methods of preventing and/or treating temporal lobe epilepsy | PRINCETON UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |