Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GUSB | P08236 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23093451 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2THRBL3MBTL1 | |
| SCHEMBL8422362 | 0.79 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2L3MBTL1GUSBPOLB | |
| SCHEMBL15658306 | 0.78 | GUSB (0.56) | ALDH1A1LMNASMN1; SMN2GUSBALDH3A1 | |
| SCHEMBL7015594 | 0.78 | GUSB (0.66) | ALDH1A1LMNASMN1; SMN2L3MBTL1GUSB | |
| SCHEMBL1818818 | 0.77 | CA1 (0.61) | SMN1; SMN2GUSBGAAHSD17B1HSD17B2 | |
| SCHEMBL8426004 | 0.76 | GAA (0.57) | LMNASMN1; SMN2GUSBMEN1KMT2A | |
| SCHEMBL8425835 | 0.75 | MEN1 (0.56) | ALDH1A1LMNASMN1; SMN2L3MBTL1GUSB | |
| SCHEMBL28270327 | 0.75 | GUSB (0.56) | ALDH1A1SMN1; SMN2L3MBTL1GUSBPOLB | |
| SCHEMBL15660019 | 0.75 | GUSB (0.56) | ALDH1A1SMN1; SMN2L3MBTL1GUSBMEN1 | |
| SCHEMBL15661006 | 0.75 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2L3MBTL1GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1241994-A | Substituted propionyl derivatives | DAIICHI SEIYAKU CO (JP) | 2000-01-19 | — | — | CN | disclosed |
| EP-0949238-A1 | SUBSTITUTED PROPIONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |