SCHEMBL8423997

SCHEMBL8423997

CC(c1ccc(Cl)cc1)c1cccc(C(=O)O)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
KDM4E B2RXH2 3/20 0.45
HSD17B10 Q99714 2/20 0.45
HPGD P15428 1/20 0.45
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
GAA P10253 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
NR4A1 P22736 1/20 0.41
ALB P02768 1/20 0.41
MMP2 P08253 1/20 0.41
HNF4A P41235 1/20 0.39
TSHR P16473 2/20 0.39
RXFP1 Q9HBX9 1/20 0.39
SELPLG Q14242 1/20 0.39
PDE5A O76074 1/20 0.39
PDE1A P54750 1/20 0.39
PDE1B Q01064 1/20 0.39
PDE4D Q08499 1/20 0.39
PDE7A Q13946 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8428221 0.88 ALDH1A1 (0.57) ALDH1A1KDM4EHSD17B10HPGDKMT2A
SCHEMBL5888693 0.88 ALDH1A1 (0.49) ALDH1A1KDM4EHSD17B10HPGDKMT2A
SCHEMBL312797 0.87 ALDH1A1 (0.50) ALDH1A1KDM4EHSD17B10HPGDKMT2A
SCHEMBL1858272 0.86 ALDH1A1 (0.49) ALDH1A1KDM4EHSD17B10HPGDKMT2A
SCHEMBL14124061 0.81 AKR1C2 (0.43) ALDH1A1KDM4EHSD17B10HPGDKMT2A
SCHEMBL3867410 0.78 ALDH1A1 (0.49) ALDH1A1KDM4EHSD17B10HPGDKMT2A
SCHEMBL4319327 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EHSD17B10HPGDKMT2A
SCHEMBL31011017 0.77 HPGD (0.61) ALDH1A1KDM4EHSD17B10HPGDKMT2A
SCHEMBL39140 0.77 HPGD (0.61) ALDH1A1KDM4EHSD17B10HPGDKMT2A
SCHEMBL11109818 0.76 TYR (0.44) ALDH1A1KDM4EHSD17B10HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0547629-B2 Color developers and sheets thereof SANYO CHEMICAL IND LTD (JP) 1999-10-27 EP disclosed