SCHEMBL8428221

SCHEMBL8428221

CC(c1ccc(O)cc1)c1cccc(C(=O)O)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
KMT2A Q03164 2/20 0.57
GAA P10253 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
HPGD P15428 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HSD17B10 Q99714 1/20 0.47
ESR1 P03372 1/20 0.47
PDCD1 Q15116 1/20 0.47
ESR2 Q92731 1/20 0.47
CD274 Q9NZQ7 1/20 0.47
ALB P02768 1/20 0.43
MMP2 P08253 1/20 0.43
TYR P14679 1/20 0.42
HNF4A P41235 1/20 0.41
IDE P14735 1/20 0.41
PARP1 P09874 1/20 0.38
CYP3A4 P08684 2/20 0.38
HMGB1 P09429 2/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5888693 0.90 ALDH1A1 (0.49) ALDH1A1KMT2AGAATDP1HPGD
SCHEMBL312797 0.90 ALDH1A1 (0.50) ALDH1A1KMT2AGAATDP1HPGD
SCHEMBL1858272 0.89 ALDH1A1 (0.49) ALDH1A1KMT2AGAATDP1HPGD
SCHEMBL8423997 0.88 ALDH1A1 (0.45) ALDH1A1KMT2AGAATDP1HPGD
SCHEMBL3867410 0.81 ALDH1A1 (0.49) ALDH1A1KMT2AGAATDP1HPGD
SCHEMBL4319327 0.80 ALDH1A1 (0.47) ALDH1A1KMT2AGAATDP1HPGD
SCHEMBL39140 0.79 HPGD (0.61) ALDH1A1KMT2AGAATDP1HPGD
SCHEMBL31011017 0.79 HPGD (0.61) ALDH1A1KMT2AGAATDP1HPGD
SCHEMBL11109818 0.79 TYR (0.44) ALDH1A1KMT2AGAATDP1HPGD
SCHEMBL1039957 0.78 ALDH1A1 (0.55) ALDH1A1KMT2AGAATDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0547629-B2 Color developers and sheets thereof SANYO CHEMICAL IND LTD (JP) 1999-10-27 EP disclosed