Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SCN2B | O60939 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428107 | 0.92 | PKM (0.37) | GABRA2GABRB2PKMNOTUMSCN2B | |
| SCHEMBL8424639 | 0.90 | GABRA2 (0.34) | GABRA2GABRB2PKMNOTUMSCN2B | |
| SCHEMBL8423316 | 0.87 | USP2 (0.34) | NOTUMUSP2POLB | |
| SCHEMBL8427940 | 0.87 | CNR2 (0.35) | GABRA2GABRB2PKMNOTUMSCN2B | |
| SCHEMBL8425430 | 0.86 | NPC1 (0.42) | ALDH1A1GAAMAPTRAB9AHPGD | |
| SCHEMBL8424239 | 0.85 | CNR2 (0.44) | NOTUMSCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL8424553 | 0.83 | CNR1 (0.39) | NOTUMRAB9ANPC1CNR2POLB | |
| SCHEMBL8424212 | 0.79 | AR (0.37) | NOTUMTP53MAPTUSP2POLB | |
| SCHEMBL8425765 | 0.79 | RAB9A (0.40) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL2863487 | 0.79 | HPGD (0.43) | MEN1KMT2AALDH1A1HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636616-B1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-10-27 | — | — | EP | disclosed |
| US-5484933-A | Process for production of fluoroalkane carboxamide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0636616-A1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-01 | — | — | EP | disclosed |