SCHEMBL8424381

SCHEMBL8424381

NC(=O)C[C@H](N)C(=O)NCCCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.44
PTGS1 P23219 1/20 0.43
KCNH2 Q12809 1/20 0.43
RRM1 P23921 1/20 0.41
GNAI3 P08754 1/20 0.39
GNAO1 P09471 1/20 0.39
GNAI1 P63096 1/20 0.39
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
ECE1 P42892 1/20 0.38
S1PR2 O95136 2/20 0.36
S1PR1 P21453 2/20 0.36
S1PR3 Q99500 2/20 0.36
S1PR5 Q9H228 1/20 0.36
ALDH1A2 O94788 1/20 0.36
ALDH2 P05091 1/20 0.36
ALDH1A3 P47895 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28778529 1.00 DPP7 (0.44) DPP7PTGS1KCNH2RRM1GNAI3
SCHEMBL453917 0.88 MEN1 (0.50) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL8230008 0.88 MEN1 (0.50) DPP7RRM1GNAI3GNAO1GNAI1
Phenol SCHEMBL29174218 0.85 ALDH1A1 (0.41) ALDH1A1PDK2
SCHEMBL1374079 0.85 DPP7 (0.44) DPP7PTGS1KCNH2RRM1GNAI3
SCHEMBL5368120 0.83 DPP7 (0.61) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL1879955 0.83 DPP7 (0.43) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL8420560 0.81 USP2 (0.39) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL29481114 0.81 ECE1 (0.50) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL1976980 0.80 DPP7 (0.67) DPP7RRM1GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8907045-B2 Biocompatible adhesive polymers EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-09 US claimed
US-8691284-B2 Fluorinated block co-polymers EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-04-08 US claimed
US-20140041802-A1 BIOCOMPATIBLE ADHESIVE POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-02-13 US claimed
WO-2013151537-A1 BIOCOMPATIBLE ADHESIVE POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-10-10 WO claimed
WO-2013006173-A1 FLUORINATED BLOCK CO-POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-01-10 WO claimed
US-20130011487-A1 FLUORINATED BLOCK CO-POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2013-01-10 US claimed
US-5858244-A COPOLYMER COMPRISING AT LEAST ONE OF N-OXYGENATEDHYDROCARBONAMIDE MONOMERS AND AT LEAST ONE OF AMINO ACID MONOMERS, POLYSUCCINIMIDES NALCO CHEMICAL COMPANY (US) 1999-01-12 US claimed
US-5776875-A Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-07-07 US claimed
EP-0819653-A2 Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-01-21 EP claimed
US-8907045-B2 Biocompatible adhesive polymers EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-09 US disclosed
US-8691284-B2 Fluorinated block co-polymers EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-04-08 US disclosed
US-20140041802-A1 BIOCOMPATIBLE ADHESIVE POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-02-13 US disclosed
WO-2013151537-A1 BIOCOMPATIBLE ADHESIVE POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-10-10 WO disclosed
WO-2013006173-A1 FLUORINATED BLOCK CO-POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-01-10 WO disclosed
US-20130011487-A1 FLUORINATED BLOCK CO-POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2013-01-10 US disclosed
US-5858244-A COPOLYMER COMPRISING AT LEAST ONE OF N-OXYGENATEDHYDROCARBONAMIDE MONOMERS AND AT LEAST ONE OF AMINO ACID MONOMERS, POLYSUCCINIMIDES NALCO CHEMICAL COMPANY (US) 1999-01-12 US disclosed
US-5776875-A Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-07-07 US disclosed
EP-0819653-A2 Use of biodegradable polymers in preventing scale build-up NALCO CHEMICAL COMPANY (US) 1998-01-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130011487-A1 FLUORINATED BLOCK CO-POLYMERS SLC1A5, FGB, SLC43A1 DPP7 4291/4885PTGS1 4143/4885KCNH2 4085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.