Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420326 | 0.88 | TSHR (0.43) | TSHRALDH1A1HSD17B10GAAKMT2A | |
| SCHEMBL8421330 | 0.86 | SMN1; SMN2 (0.46) | TSHRALDH1A1HSD17B10GAAKMT2A | |
| SCHEMBL30000915 | 0.82 | ALDH1A1 (0.44) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL8424504 | 0.82 | PTGDR2 (0.42) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9279878 | 0.81 | PTGDR2 (0.41) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL18749585 | 0.81 | MRGPRX4 (0.45) | TSHRKDM4EKMT2AMEN1LMNA | |
| SCHEMBL8519544 | 0.81 | PTGDR2 (0.38) | TSHRALDH1A1KMT2AMEN1PTGDR2 | |
| SCHEMBL18749686 | 0.78 | PTGDR2 (0.39) | TSHRALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL896797 | 0.78 | SMN1; SMN2 (0.40) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL8399059 | 0.78 | SMN1; SMN2 (0.40) | TSHRALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948819-A | α-substituted phenylacetic acid derivative, its production and agricultural fungicide containing it | SHIONOGI & CO., LTD (JP) | 1999-09-07 | — | — | US | disclosed |