Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.36 |
| ▸ | AR | P10275 | 5/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407074 | 0.89 | PGR (0.33) | PGRNR3C1ARAKR1C3 | |
| SCHEMBL9174030 | 0.83 | MAPT (0.42) | AKR1C3CYP3A4 | |
| SCHEMBL5891654 | 0.81 | AKR1C3 (0.34) | PGRNR3C1ARAKR1C3CYP3A4 | |
| SCHEMBL7868038 | 0.81 | AKR1C3 (0.34) | PGRNR3C1ARAKR1C3CYP3A4 | |
| SCHEMBL6864127 | 0.81 | AKR1C3 (0.33) | PGRAKR1C3 | |
| SCHEMBL8427011 | 0.80 | PGR (0.47) | PGRNR3C1AR | |
| SCHEMBL5891671 | 0.80 | AKR1C3 (0.33) | PGRNR3C1ARAKR1C3 | |
| SCHEMBL5891664 | 0.76 | AKR1C3 (0.46) | AKR1C3CYP3A4 | |
| SCHEMBL8407252 | 0.76 | PGR (0.37) | PGRNR3C1AR | |
| SCHEMBL8768906 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582338-B1 | 17-Spiromethylene steroids | AKZO NOBEL NV (NL) | 1999-10-20 | — | — | EP | disclosed |
| EP-0582338-A2 | 17-Spiromethylene steroids | Akzo Nobel N.V. (NL) | 1994-02-09 | — | — | EP | disclosed |