Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.32 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5891966 | 0.91 | PGR (0.36) | PGRNR3C1ARPOLBMAPT | |
| SCHEMBL8407179 | 0.91 | PGR (0.36) | PGRNR3C1ARPOLBMAPT | |
| SCHEMBL8410110 | 0.91 | PGR (0.36) | PGRNR3C1ARPOLBMAPT | |
| SCHEMBL8410127 | 0.88 | PGR (0.47) | PGRNR3C1ARPOLBMAPT | |
| SCHEMBL8407074 | 0.87 | PGR (0.33) | PGRNR3C1ARPOLBMAPT | |
| SCHEMBL6864127 | 0.84 | AKR1C3 (0.33) | PGR | |
| SCHEMBL8653835 | 0.83 | MAPT (0.46) | PGRPOLBMAPT | |
| SCHEMBL8769024 | 0.82 | PGR (0.30) | PGRPOLBMAPT | |
| SCHEMBL8407329 | 0.81 | POLB (0.35) | ARPOLBMAPT | |
| SCHEMBL8768992 | 0.81 | PGR (0.32) | PGRNR3C1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| EP-0567469-B1 | 14beta-H-, 14- AND 15-EN-11beta-ARYL-4-ESTRENES | SCHERING AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5519027-A | PROGESTERONE ANTAGONIST FOR OXYTOCICS OR PREVENTION OF TERMINATION OF PREGNANCY | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |
| US-5426102-A | Antigestagenic, antiandrogenic, antiglucocorticoid, antimineralcorticoid properties | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-20 | — | — | US | disclosed |
| US-5405601-A | Functionalized tripodal ligands for imaging applications | MALLINCKRODT MEDICAL INC. (US) | 1995-04-11 | — | — | US | disclosed |
| US-5405979-A | Stereoselectively reducing phenyl-substituted estradiene with electropositive metal in electron-solvating solvent, cleaving ketone protective group with acid | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | disclosed |
| EP-0532562-B1 | PROCESS FOR PRODUCING 10$g(b)-H-STEROIDS | SCHERING AG (DE) | 1994-11-23 | — | — | EP | disclosed |
| WO-1991018918-A1 | PROCESS FOR PRODUCING 10β-H-STEROIDS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-12-12 | — | — | WO | disclosed |