Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864127 | 0.92 | AKR1C3 (0.33) | PGRAKR1C3 | |
| SCHEMBL8425100 | 0.89 | PGR (0.47) | PGRAKR1C3NR3C1AR | |
| SCHEMBL8407252 | 0.87 | PGR (0.37) | PGRNR3C1ARPOLBMAPT | |
| SCHEMBL9174030 | 0.85 | MAPT (0.42) | AKR1C3POLBMAPT | |
| SCHEMBL8407179 | 0.84 | PGR (0.36) | PGRNR3C1ARPOLBMAPT | |
| SCHEMBL8410110 | 0.84 | PGR (0.36) | PGRNR3C1ARPOLBMAPT | |
| SCHEMBL5891966 | 0.84 | PGR (0.36) | PGRNR3C1ARPOLBMAPT | |
| SCHEMBL5891671 | 0.82 | AKR1C3 (0.33) | PGRAKR1C3NR3C1AR | |
| SCHEMBL5891654 | 0.82 | AKR1C3 (0.34) | PGRAKR1C3NR3C1AR | |
| SCHEMBL7868038 | 0.82 | AKR1C3 (0.34) | PGRAKR1C3NR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| US-5405979-A | Stereoselectively reducing phenyl-substituted estradiene with electropositive metal in electron-solvating solvent, cleaving ketone protective group with acid | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | disclosed |
| EP-0532562-B1 | PROCESS FOR PRODUCING 10$g(b)-H-STEROIDS | SCHERING AG (DE) | 1994-11-23 | — | — | EP | disclosed |