Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425149 | 0.86 | MAPKAPK2 (0.37) | MAPKAPK2FFAR4FFAR1 | |
| SCHEMBL8426672 | 0.81 | S1PR1 (0.39) | FFAR4FFAR1CA2ITGB3ITGA2B | |
| SCHEMBL8425962 | 0.80 | CA2 (0.49) | CA2 | |
| SCHEMBL8428904 | 0.78 | GRIN2B (0.38) | GRIN2B | |
| SCHEMBL16650295 | 0.78 | CA2 (0.38) | CA2ITGB3ITGA2BGRIN2BESR1 | |
| SCHEMBL6351624 | 0.78 | MLNR (0.39) | FFAR4KCNH2CA2ITGB3ITGA2B | |
| SCHEMBL25427665 | 0.78 | S1PR1 (0.48) | KCNH2S1PR1SGPL1S1PR3 | |
| SCHEMBL8425112 | 0.78 | FFAR4 (0.39) | FFAR4FFAR1CA2ITGB3ITGA2B | |
| SCHEMBL8425111 | 0.78 | FFAR4 (0.39) | FFAR4FFAR1CA2ITGB3ITGA2B | |
| SCHEMBL8429563 | 0.78 | FFAR4 (0.39) | FFAR4FFAR1CA2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925662-A | OXIDASE INHIBITORS | SYNTHELABO (FR) | 1999-07-20 | — | — | US | disclosed |