Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543379 | 0.84 | ALDH1A1 (0.37) | PKMHPGDSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6209101 | 0.82 | CPA3 (0.51) | HPGDLTA4H | |
| SCHEMBL6209106 | 0.82 | CPA3 (0.51) | HPGDLTA4H | |
| SCHEMBL10883595 | 0.82 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL27282127 | 0.80 | ALPI (0.53) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL7775515 | 0.77 | CYP2C19 (0.40) | PKMPTGS1HPGD | |
| SCHEMBL7775511 | 0.77 | CYP2C19 (0.40) | PKMPTGS1HPGD | |
| SCHEMBL3836356 | 0.76 | ALOX5 (0.47) | PKMPTGS1HPGDSLC1A3SLC1A2 | |
| SCHEMBL7451001 | 0.75 | ALDH1A1 (0.43) | HPGDSLC1A3SLC1A2SLC1A1SLC15A1 | |
| SCHEMBL7440888 | 0.75 | ALDH1A1 (0.43) | HPGDSLC1A3SLC1A2SLC1A1SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005071-A | SPECIFIC REGION OF HIRUDIN THAT IS RESPONSIBLE, AT LEAST IN PART, FOR ITS ANTICOAGULANT ACTIVITY | MERRELL PHARMACEUTICALS INC. (US) | 1999-12-21 | — | — | US | disclosed |