Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425491 | 1.00 | GAA (0.43) | GAATSHRAMY1AKMT2AL3MBTL1 | |
| SCHEMBL8011684 | 0.95 | GAA (0.47) | GAATSHRAMY1AKMT2AL3MBTL1 | |
| SCHEMBL8011682 | 0.95 | GAA (0.47) | GAATSHRAMY1AKMT2AL3MBTL1 | |
| SCHEMBL8423941 | 0.85 | KMT2A (0.54) | GAAAMY1AKMT2AL3MBTL1MEN1 | |
| SCHEMBL8423937 | 0.85 | KMT2A (0.54) | GAAAMY1AKMT2AL3MBTL1MEN1 | |
| SCHEMBL8423664 | 0.83 | KMT2A (0.42) | GAATSHRKMT2AL3MBTL1NPSR1 | |
| SCHEMBL8423662 | 0.83 | KMT2A (0.42) | GAATSHRKMT2AL3MBTL1NPSR1 | |
| SCHEMBL8424072 | 0.81 | KMT2A (0.43) | GAAAMY1AKMT2AL3MBTL1MAPT | |
| SCHEMBL8424070 | 0.81 | KMT2A (0.43) | GAAAMY1AKMT2AL3MBTL1MAPT | |
| SCHEMBL8425493 | 0.80 | GAA (0.46) | GAAAMY1AKMT2AL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |