Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427622 | 0.69 | IDO1 (0.40) | IDO1PAMPTGER4PTGER3PTGER2 | |
| SCHEMBL2034451 | 0.69 | IDO1 (0.47) | IDO1PAMPTGER4PTGER3PTGER2 | |
| SCHEMBL2034448 | 0.69 | IDO1 (0.47) | IDO1PAMPTGER4PTGER3PTGER2 | |
| SCHEMBL163963 | 0.68 | MAOB (0.67) | IDO1PAMPTGER4PTGER3PTGER2 | |
| SCHEMBL1892917 | 0.68 | MAOB (0.67) | IDO1PAMPTGER4PTGER3PTGER2 | |
| SCHEMBL4256257 | 0.68 | MAOB (0.67) | IDO1PAMPTGER4PTGER3PTGER2 | |
| SCHEMBL216992 | 0.67 | CALM1 (0.46) | IDO1HTR2AALDH1A1MAOBADRA2C | |
| SCHEMBL10599724 | 0.67 | PTGER4 (0.50) | IDO1PAMPTGER4PTGER3PTGER2 | |
| SCHEMBL10599731 | 0.67 | PTGER4 (0.50) | IDO1PAMPTGER4PTGER3PTGER2 | |
| SCHEMBL4863423 | 0.66 | IDO1 (0.58) | IDO1PAMHTR2AALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912311-A | Olefin polymerization method comprising allyl-cycloalkadienyl dianions as catalyst precursors | UNIVATION TECHNOLOGIES, LLC | 1999-06-15 | — | — | US | disclosed |
| US-5866497-A | Catalyst for the production of olefin polymers | UNIVATION TECHNOLOGIES LLC (US) | 1999-02-02 | — | — | US | disclosed |
| US-5700748-A | Catalyst for the production of olefin polymers comprising a bridging allyl-cyclodienyl ligand on a metal atom | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-12-23 | — | — | US | disclosed |
| EP-0771777-A1 | Catalyst precursor for the production of olefin polymers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-05-07 | — | — | EP | disclosed |