SCHEMBL8425645

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31279599	0.89	NOS3 (0.61)	CCR1CCR5CCR8NOS2NOS3
	SCHEMBL913143	0.89	NOS3 (0.61)	CCR1CCR5CCR8NOS2NOS3
	SCHEMBL17132035	0.89	CCR1 (0.63)	CCR1CCR5CCR8NOS2NOS3
	SCHEMBL23037127	0.86	CCR1 (0.71)	CCR1CCR5CCR8NOS2NOS3
	SCHEMBL29693673	0.86	CCR1 (0.71)	CCR1CCR5CCR8NOS2NOS3
	SCHEMBL15082607	0.86	CCR1 (0.71)	CCR1CCR5CCR8NOS2NOS3
	SCHEMBL181893	0.82	CCR1 (1.00)	CCR1CCR5CCR8NOS2NOS3
	SCHEMBL29397106	0.82	CCR1 (1.00)	CCR1CCR5CCR8NOS2NOS3
	SCHEMBL5468413	0.82	CCR1 (0.65)	CCR1CCR5CCR8NOS2NOS3
	SCHEMBL29680018	0.82	CCR1 (0.65)	CCR1CCR5CCR8NOS2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.