Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.71 |
| ▸ | CCR5 | P51681 | 2/20 | 0.71 |
| ▸ | CCR8 | P51685 | 2/20 | 0.71 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29693673 | 0.88 | CCR1 (0.71) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL23037127 | 0.88 | CCR1 (0.71) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL8425645 | 0.86 | CCR1 (0.68) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL6882727 | 0.85 | CCR1 (0.61) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL181893 | 0.84 | CCR1 (1.00) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL29397106 | 0.84 | CCR1 (1.00) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL29680018 | 0.84 | CCR1 (0.65) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL29693626 | 0.84 | CCR1 (0.65) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL29978828 | 0.84 | CCR1 (0.65) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL3958545 | 0.84 | CCR1 (0.65) | CCR1CCR5CCR8METAP2UHRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130172308-A1 | ANTIMICROBIAL AGENTS | JOHN GRANT COLLINS (AU) | 2013-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172308-A1 | ANTIMICROBIAL AGENTS | IMMT, NDUFS5, MT-ND5 | CCR1 2232/4885CCR5 881/4885CCR8 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.