Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.60 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | TK2 | O00142 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922838 | 0.94 | TK1 (0.67) | TK1RNASE1TK2 | |
| SCHEMBL7922840 | 0.94 | TK1 (0.67) | TK1RNASE1TK2 | |
| SCHEMBL8426252 | 0.91 | TK1 (0.49) | TK1RNASE1TOP2A | |
| SCHEMBL22983968 | 0.90 | TYMS (0.56) | TK1 | |
| SCHEMBL7535874 | 0.90 | TYMS (0.56) | TK1 | |
| SCHEMBL23649887 | 0.90 | RNASE1 (0.47) | TK1RNASE1TOP2A | |
| SCHEMBL2460809 | 0.90 | TYMS (0.56) | TK1 | |
| SCHEMBL22983972 | 0.90 | TYMS (0.56) | TK1 | |
| SCHEMBL2460807 | 0.90 | TYMS (0.56) | TK1 | |
| SCHEMBL22984023 | 0.90 | TYMS (0.56) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5892024-A | Bifunctional nucleosides, oligomers thereof, and methods of making and using the same | SANOFI (FR) | 1999-04-06 | — | — | US | disclosed |