Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652014 | 0.86 | — | — | |
| SCHEMBL6176473 | 0.81 | ALDH1A1 (0.33) | — | |
| SCHEMBL10356415 | 0.80 | DNM1 (0.36) | SPHK1USP2HTT | |
| SCHEMBL6179598 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL8541219 | 0.79 | ALDH1A1 (0.40) | SPHK1USP2HTT | |
| SCHEMBL6177175 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL1498138 | 0.78 | — | — | |
| SCHEMBL29290756 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL28840564 | 0.76 | LMNA (0.42) | — | |
| SCHEMBL11084823 | 0.76 | HTT (0.48) | SPHK1USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942641-A | TREATMENT OF ALZHEIMER'S DISEASE, NERVOUS SYSTEM DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-24 | — | — | US | disclosed |