Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.63 |
| ▸ | DRD3 | P35462 | 5/20 | 0.63 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426184 | 1.00 | DRD2 (0.63) | DRD2DRD3TMEM97SIGMAR1ACKR3 | |
| SCHEMBL8426019 | 0.97 | DRD3 (0.67) | DRD2DRD3TMEM97SIGMAR1ACKR3 | |
| SCHEMBL8426018 | 0.97 | DRD3 (0.67) | DRD2DRD3TMEM97SIGMAR1ACKR3 | |
| SCHEMBL8425898 | 0.94 | DRD2 (0.57) | DRD2DRD3TMEM97SIGMAR1LMNA | |
| SCHEMBL8425893 | 0.94 | DRD2 (0.57) | DRD2DRD3TMEM97SIGMAR1LMNA | |
| SCHEMBL9263247 | 0.85 | PRMT5 (0.59) | DRD2DRD3PRMT5WDR77CYP1A2 | |
| SCHEMBL9263228 | 0.85 | PRMT5 (0.59) | DRD2DRD3PRMT5WDR77CYP1A2 | |
| SCHEMBL8333005 | 0.84 | DRD2 (0.50) | DRD2DRD3SIGMAR1LMNAOPRM1 | |
| SCHEMBL8333009 | 0.84 | DRD2 (0.50) | DRD2DRD3SIGMAR1LMNAOPRM1 | |
| SCHEMBL8428415 | 0.84 | DRD3 (0.53) | DRD2DRD3LMNAPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891877-A | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR | XENOVA LIMITED (GB) | 1999-04-06 | — | — | US | disclosed |
| WO-1995021832-A1 | PHARMACEUTICAL PIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1995-08-17 | — | — | WO | disclosed |