Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 6/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426186 | 1.00 | KMT2A (0.48) | KMT2ARAB9AMAPTNPC1MEN1 | |
| SCHEMBL8426183 | 1.00 | KMT2A (0.48) | KMT2ARAB9AMAPTNPC1MEN1 | |
| SCHEMBL6376088 | 0.90 | SERPINE1 (0.56) | KMT2ARAB9AMAPTNPC1MEN1 | |
| SCHEMBL6376092 | 0.90 | SERPINE1 (0.56) | KMT2ARAB9AMAPTNPC1MEN1 | |
| SCHEMBL6373314 | 0.79 | ALDH1A1 (0.46) | KMT2ARAB9AMAPTNPC1MEN1 | |
| SCHEMBL6374742 | 0.78 | LRRK2 (0.55) | KMT2ARAB9AMAPTNPC1MEN1 | |
| SCHEMBL6374734 | 0.78 | LRRK2 (0.55) | KMT2ARAB9AMAPTNPC1MEN1 | |
| SCHEMBL8596135 | 0.78 | KMT2A (0.53) | KMT2ARAB9AMAPTNPC1MEN1 | |
| SCHEMBL8596133 | 0.78 | KMT2A (0.53) | KMT2ARAB9AMAPTNPC1MEN1 | |
| SCHEMBL8424998 | 0.78 | RELA (0.51) | KMT2ARAB9AMAPTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021832-A1 | PHARMACEUTICAL PIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1995-08-17 | — | — | WO | claimed |
| US-5891877-A | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR | XENOVA LIMITED (GB) | 1999-04-06 | — | — | US | disclosed |
| WO-1995021832-A1 | PHARMACEUTICAL PIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1995-08-17 | — | — | WO | disclosed |