SCHEMBL8426286

SCHEMBL8426286

CC(=CC(C)O)C(=O)O.CCC(O)C=C(C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAPDH P04406 1/20 0.33
PTPN11 Q06124 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16667 0.92 GAPDH (0.38) GAPDHPTPN11
SCHEMBL711050 0.92 GAPDH (0.38) GAPDHPTPN11
SCHEMBL16093 0.85
SCHEMBL37709 0.85
Phosphoric Acid SCHEMBL21408816 0.84 GRIN2D (0.34) GAPDHPTPN11
Succinic Acid SCHEMBL17363356 0.83 LMNA (0.42)
Acetone SCHEMBL8337337 0.83 TP53 (0.36)
SCHEMBL28181082 0.83 TP53 (0.36)
SCHEMBL10753894 0.82 GAPDH (0.32) GAPDHPTPN11
SCHEMBL9781496 0.82 GRIK1 (0.34) GAPDHPTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5965632-A CURABLE IONOMER PASTE COMPRISING A MIXTURE OF AN AQUEOUS SUSPENSION OF ACRYLIC ACID HOMO- OR COPOLYMER AND FILLER AND AN ACID-THICKENED AQUEOUS PASTE OF ALKALINE GLASS FLUX; EASE IN HANDLING; ACCURATE DISPENSING; STRENGTH; FLUORIDE RELEASE SCIENTIFIC PHARMACEUTICALS INC. (US) 1999-10-12 US disclosed
US-4314044-A Process for preparing low molecular weight water-soluble polymers ROHM AND HAAS COMPANY (US) 1982-02-02 US disclosed
EP-0014083-A1 Low molecular weight watersoluble polymers, their preparation and their use in scale inhibition ROHM AND HAAS COMPANY (US) 1980-08-06 EP disclosed