Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8334356 | 0.99 | SIGMAR1 (0.38) | SLC9A1JUNNFKB1NFKB2RELA | |
| SCHEMBL9018692 | 0.82 | SLC9A1 (0.41) | SLC9A1SLC9A5 | |
| SCHEMBL8428554 | 0.81 | SLC9A1 (0.44) | SLC9A1ITGB3ITGAV | |
| Hydrochloric Acid SCHEMBL8333010 | 0.80 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL8426429 | 0.78 | JUN (0.39) | JUNNFKB1NFKB2RELASIGMAR1 | |
| SCHEMBL8428569 | 0.77 | SLC9A1 (0.40) | SLC9A1ITGB3ITGAV | |
| SCHEMBL8332067 | 0.77 | NOTUM (0.48) | JUNNFKB1NFKB2RELA | |
| SCHEMBL8430504 | 0.77 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL8430500 | 0.77 | SLC9A1 (0.42) | SLC9A1ITGB3ITGAV | |
| Hydrochloric Acid SCHEMBL8334351 | 0.77 | JUN (0.39) | JUNNFKB1NFKB2RELASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791577-B1 | Ortho-substituted benzylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicament containing them | HOECHST AG (DE) | 1999-11-03 | — | — | EP | claimed |