Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | BCHE | P06276 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 2/20 | 0.48 |
| ▸ | FNTB | P49356 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428563 | 0.88 | BCHE (0.65) | MAPTBCHEGAAPPARGNPSR1 | |
| SCHEMBL8426652 | 0.85 | BCHE (0.67) | MAPTBCHEGAAPPARGNPSR1 | |
| SCHEMBL3240026 | 0.81 | MAPT (0.58) | MAPTBCHEGAAPPARGMEN1 | |
| SCHEMBL9423724 | 0.78 | NOX1 (0.59) | MAPTBCHEGAAMEN1KMT2A | |
| SCHEMBL15775131 | 0.77 | PPARG (0.71) | MAPTBCHEGAAPPARGNPSR1 | |
| SCHEMBL12311066 | 0.76 | MEN1 (0.69) | MAPTBCHEPPARGMEN1KMT2A | |
| SCHEMBL15775176 | 0.76 | PPARG (0.70) | MAPTBCHEGAAPPARGMEN1 | |
| SCHEMBL12896373 | 0.76 | MAPT (0.63) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL29923275 | 0.76 | MAPT (0.63) | MAPTNPSR1MEN1KMT2AKDM4E | |
| SCHEMBL8435143 | 0.76 | FNTA (0.66) | MAPTGAANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861394-A | COMPOUNDS AS ANTIISCHEMIC AGENTS, TREATMENT OF STROKES, ANTIHEMORRHEGENIC AGENTS, ANTIDEPRESSANTS OR TREATMENT OF SICKKLE CELL ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | claimed |