SCHEMBL842668

SCHEMBL842668

SCCCc1ccncc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.56
LOXL2 Q9Y4K0 2/20 0.52
HRH3 Q9Y5N1 3/20 0.47
HRH4 Q9H3N8 2/20 0.47
NAAA Q02083 1/20 0.46
CYP3A4 P08684 6/20 0.42
CYP1A2 P05177 5/20 0.42
CYP2D6 P10635 5/20 0.42
CYP2C9 P11712 5/20 0.42
CYP2C19 P33261 4/20 0.42
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HIF1A Q16665 1/20 0.41
NPC1 O15118 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL842664 0.93 HRH1 (0.59) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL272061 0.91 HRH1 (0.63) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL73482 0.84
SCHEMBL726645 0.84 HRH1 (0.73) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL351920 0.84 HRH1 (0.65) HRH1LOXL2HRH3HRH4NAAA
Hydrochloric Acid SCHEMBL258153 0.82 LOXL2 (0.54) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL2841394 0.81 HRH1 (0.77) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL4413800 0.81 HRH1 (0.77) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL31673871 0.81 HRH1 (0.62) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL28055322 0.81 HRH1 (0.62) HRH1LOXL2HRH3HRH4NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117966225-B QFP blister copper electroplating solution, preparation method and electroplating method 昆山一鼎工业科技有限公司 2024-07-16 CN claimed
US-6946581-B2 Bisphenol compound composition having excellent thermal stability MITSUBISHI CHEMICAL CORPORATION (JP) 2005-09-20 US claimed
EP-2948771-B1 CHEMICAL SENSING DEVICE HEWLETT PACKARD DEVELOPMENT CO (US) 2019-04-10 EP disclosed
US-20190077894-A1 PROCESS FOR PREPARING CATALYSTS LANXESS DEUTSCHLAND GMBH (DE) 2019-03-14 US disclosed
EP-2952256-B1 METHOD FOR THE PRODUCTION OF CATALYSTS LANXESS DEUTSCHLAND GMBH (DE) 2017-05-17 EP disclosed
US-20150362433-A1 CHEMICAL SENSING DEVICE HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2015-12-17 US disclosed
US-20150353660-A1 PROCESS FOR PREPARING CATALYSTS LANXESS DEUTSCHLAND GMBH (DE) 2015-12-10 US disclosed
EP-2952256-A1 METHOD FOR THE PRODUCTION OF CATALYSTS LANXESS Deutschland GmbH (DE) 2015-12-09 EP disclosed
EP-2948771-A1 CHEMICAL SENSING DEVICE Hewlett-Packard Development Company L.P. (US) 2015-12-02 EP disclosed
CN-104937416-A Chemical sensing device HEWLETT PACKARD DEVELOPMENT CO 2015-09-23 CN disclosed
US-8932976-B2 Preparation of catalyst for bisphenols production DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-13 US disclosed
US-6051569-A 1'S, 5R, 6R-carbapenem derivatives and antimicrobial agents comprising the same SUNTORY LIMITED (JP) 2000-04-18 US disclosed
EP-0826687-A1 Carbapenem derivatives and antimicrobial agents comprising the same SUNTORY LIMITED (JP) 1998-03-04 EP disclosed
EP-0774465-A1 Penem derivatives and antimicrobial agents containing the same SUNTORY LIMITED (JP) 1997-05-21 EP disclosed
EP-0757051-A1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME SUNTORY LIMITED (JP) 1997-02-05 EP disclosed
EP-0168707-A1 1-Methylcarbapenems having a 2-quaternary heteroarylalkylthio substituent MERCK & CO. INC. (US) 1986-01-22 EP disclosed
US-4478956-A FOR CATALYTIC CONDENSATION OF PHENOL WITH KETONE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1984-10-23 US disclosed
EP-0045959-B1 PROCESS FOR PREPARING BISPHENOLS MITSUBISHI KASEI CORPORATION (JP) 1984-04-04 EP disclosed
US-4423252-A CONDENSATION OF A PHENOL WITH A KETONE IN THE PRESENCE OF A SULFONIC ACID TYDE CATION EXCHANGE RESIN MODIFIED WITH A PYRIDINE-ALKANE THIOL MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-12-27 US disclosed
EP-0045959-A1 Process for preparing bisphenols MITSUBISHI KASEI CORPORATION (JP) 1982-02-17 EP disclosed