Hydrochloric Acid

Hydrochloric Acid

SCHEMBL258153

Cl.SCCc1ccncc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HRH1 known ✓ P35367 2/20 0.46
HRH3 known ✓ Q9Y5N1 3/20 0.43
LOXL2 Q9Y4K0 2/20 0.54
CYP1A2 P05177 5/20 0.44
CYP3A4 P08684 5/20 0.44
CYP2D6 P10635 4/20 0.44
CYP2C9 P11712 4/20 0.44
CYP2C19 P33261 4/20 0.44
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HRH4 Q9H3N8 2/20 0.42
HIF1A Q16665 1/20 0.42
KDM4E B2RXH2 2/20 0.40
NAAA Q02083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL73482 0.97
Alcohol SCHEMBL29129752 0.86 LOXL2 (0.46) LOXL2HRH1CYP1A2CYP3A4CYP2D6
Formic Acid SCHEMBL8362262 0.84 LOXL2 (0.45) LOXL2HRH1CYP1A2CYP3A4CYP2D6
SCHEMBL1129624 0.83 CYP17A1 (0.52) LOXL2CYP3A4ALDH1A1HRH3
SCHEMBL842668 0.82 HRH1 (0.56) LOXL2HRH1CYP1A2CYP3A4CYP2D6
SCHEMBL842664 0.80 HRH1 (0.59) LOXL2HRH1CYP1A2CYP3A4CYP2D6
SCHEMBL151822 0.80 LOXL2 (0.68) LOXL2HRH1CYP1A2CYP3A4CYP2D6
Acetic Acid SCHEMBL29556933 0.80 TSHR (0.41) LOXL2ALDH1A1HSD17B10L3MBTL1
SCHEMBL272061 0.78 HRH1 (0.63) LOXL2HRH1CYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL1345387 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626996-A1 POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM Electronic Materials U.S.A, Inc. (US) 2025-10-08 EP claimed
WO-2024118398-A1 POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2024-06-06 WO claimed
CN-115364236-A Cell membrane anchored ROS (reactive oxygen species) -responsive chitosan gel prodrug system, preparation method and application thereof 安徽工业大学 2022-11-22 CN claimed
US-20180082762-A1 Transparent Conductive Film, Dispersion Liquid, Information Input Device, and Electronic Equipment DEXERIALS CORPORATION (JP) 2018-03-22 US claimed
CN-116180076-B Environment-friendly process applied to filling through holes of wafers 深圳创智芯联科技股份有限公司 2024-07-26 CN disclosed
CN-116180076-A Environment-friendly process applied to filling through holes of wafers 深圳创智芯联科技股份有限公司 2023-05-30 CN disclosed
CN-115477881-A Water-based wear-resistant transparent antifogging resin polymer and preparation method thereof 广东邦固化学科技有限公司 2022-12-16 CN disclosed
CN-115364236-A Cell membrane anchored ROS (reactive oxygen species) -responsive chitosan gel prodrug system, preparation method and application thereof 安徽工业大学 2022-11-22 CN disclosed
EP-3357917-A1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF Aragon Pharmaceuticals, Inc. (US) 2018-08-08 EP disclosed
US-10023556-B2 Androgen receptor modulators and uses thereof ARAGON PHARMACEUTICALS, INC. (US) 2018-07-17 US disclosed
US-9988535-B2 Thiol group-containing colored compound, metal nanowire, dispersion liquid, transparent conductive film, information input device, and electronic apparatus DEXERIALS CORPORATION (JP) 2018-06-05 US disclosed
EP-3124481-B1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF ARAGON PHARMACEUTICALS INC (US) 2018-03-28 EP disclosed
WO-2004108692-A1 SULPHONAMIDE COMPOUNDS THAT MODULATE CHEMOKINE RECEPTOR ACTIVITY (CCR4) ASTRAZENECA AB (SE) 2004-12-16 WO disclosed
EP-0891223-B1 METHODS FOR THE PREPARATION OF RESINS WITH LIGANDS ATTACHED THERETO THROUGH A LINKING GROUP COMPRISING SULFIDE, SULFOXIDE OR SULFONE FUNCTIONALITY UNIV MASSEY (NZ) 2004-10-20 EP disclosed
EP-1464391-A2 Methods for the preparation of resins with ligands attached thereto through a linking group comprising sulfide, sulfoxide, sulfone or sulfonate functionality MASSEY UNIVERSITY (NZ) 2004-10-06 EP disclosed
WO-2004073030-A2 METAL 8-HYDROXYQUINOLINE -FUNCTIONALIZED POLYMERS AND RELATED MATERIALS AND METHODS OF MAKING AND USING THE SAME GEORGIA TECH RESEARCH CORPORATION (US) 2004-08-26 WO disclosed
EP-0891223-A4 METHODS FOR THE PREPARATION OF RESINS WITH LIGANDS ATTACHED THERETO THROUGH A LINKING GROUP COMPRISING SULFIDE, SULFOXIDE, SULFONE OR SULFONATE FUNCTIONALITY UNIV MASSEY (NZ) 1999-07-28 EP disclosed
EP-0891223-A1 METHODS FOR THE PREPARATION OF RESINS WITH LIGANDS ATTACHED THERETO THROUGH A LINKING GROUP COMPRISING SULFIDE, SULFOXIDE, SULFONE OR SULFONATE FUNCTIONALITY MASSEY UNIVERSITY (NZ) 1999-01-20 EP disclosed
US-5789578-A SUPPORTS WITH CHROMATOGRAPHIC RESINS WITH SULFIDE THAT CAN BE OXIDIZED MASSEY UNIVERSITY (NZ) 1998-08-04 US disclosed
WO-1997025139-A1 METHODS FOR THE PREPARATION OF RESINS WITH LIGANDS ATTACHED THERETO THROUGH A LINKING GROUP COMPRISING SULFIDE, SULFOXIDE, SULFONE OR SULFONATE FUNCTIONALITY MASSEY UNIVERSITY (NZ) 1997-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10023556-B2 Androgen receptor modulators and uses thereof AR, ESRRA, NR5A1 HRH1 2602/4885HRH3 3256/4885LOXL2 1485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.