SCHEMBL316882

SCHEMBL316882

CN(CC(=O)O)C(=O)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
PRSS1 P07477 1/20 0.50
TPSAB1 Q15661 1/20 0.50
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
SIGMAR1 Q99720 1/20 0.46
ABCB1 P08183 1/20 0.46
MAOB P27338 1/20 0.46
CHRNB2 P17787 1/20 0.46
CHRNB4 P30926 1/20 0.46
CHRNA3 P32297 1/20 0.46
CHRNA4 P43681 1/20 0.46
LMNA P02545 1/20 0.45
HCAR2 Q8TDS4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6444517 0.98 ALDH1A1 (0.53) ALDH1A1MAPTHPGDPRSS1TPSAB1
SCHEMBL21070425 0.94 ALDH1A1 (0.49) ALDH1A1MAPTHPGDPRSS1TPSAB1
SCHEMBL21069881 0.94 ALDH1A1 (0.49) ALDH1A1MAPTHPGDPRSS1TPSAB1
SCHEMBL2621484 0.88 ALDH1A1 (0.58) ALDH1A1MAPTHPGDPRSS1TPSAB1
SCHEMBL6447135 0.88 ALDH1A1 (0.53) ALDH1A1MAPTHPGDPRSS1TPSAB1
SCHEMBL5331588 0.87 ALDH1A1 (0.51) ALDH1A1MAPTHPGDPRSS1TPSAB1
SCHEMBL15601806 0.87 PRSS1 (0.51) ALDH1A1MAPTPRSS1TPSAB1MAOB
SCHEMBL6444506 0.87 ALDH1A1 (0.56) ALDH1A1MAPTHPGDPRSS1TPSAB1
SCHEMBL10485256 0.86 PRSS1 (0.43) ALDH1A1MAPTHPGDPRSS1TPSAB1
SCHEMBL7367495 0.86 ALDH1A1 (0.58) ALDH1A1MAPTHPGDMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106456698-B Synthesis of beta-arrestin effectors 特维娜有限公司 2022-05-17 CN claimed
EP-0384341-A2 New proline derivatives KABUSHIKI KAISHA YAKULT HONSHA (JP) 1990-08-29 EP claimed
EP-4714446-A2 PHARMACEUTICAL COMPOUNDS Nxera Pharma UK Limited (GB) 2026-03-25 EP disclosed
US-12552796-B2 EED inhibitor, and preparation method therefor and use thereof JING MEDICINE TECHNOLOGY (SHANGHAI) LTD. (CN) 2026-02-17 US disclosed
EP-4056570-B1 EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF UNIV SHANGHAI TECHNOLOGY (CN) 2026-01-07 EP disclosed
US-20250368680-A1 METHOD FOR PRODUCING SALT OF AMINO ACID OR SALT OF PEPTIDE COMPOUND OR SOLVATE OF EITHER ONE OF SAID SALTS COMPRISING LITHIUM SALT PRECIPITATION STEP CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-12-04 US disclosed
EP-4653438-A1 MACROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF Genfleet Therapeutics (Shanghai) Inc. (CN) 2025-11-26 EP disclosed
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-10-23 US disclosed
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-09 US disclosed
US-20250313579-A1 LIGAND COMPOUNDS COMPRISING A CHELATING GROUP AS A BRIDGING GROUP Technische Universität München (DE) 2025-10-09 US disclosed
EP-4613773-A2 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-09-10 EP disclosed
EP-0005070-A2 N-(2-thiazolyl)amides and their use as anti-inflammatory and immunoregulatory agents PFIZER INC. (US) 1979-10-31 EP disclosed
EP-0002822-A1 Phosphorus containing peptide derivatives, their production, intermediates for their production and pharmaceutical compositions containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1979-07-11 EP disclosed
US-4155902-A ACYLATION, HYDROGENOLYSIS ABBOTT LABORATORIES (US) 1979-05-22 US disclosed
US-4124756-A REACTION WITH PROTECTED AMINO ACIDS TO FORM 3-DE-O-METHYL-N-ACYLFORTIMICINS; ANTIBACTERIAL ABBOTT LABORATORIES (US) 1978-11-07 US disclosed
US-RE29668-E 4-OXO-1,2-BENZOTHIAZINE-3-CARBOXAMIDE, 1,1-DIOXIDES, ANTIINFLAMMATORY PFIZER INC. (US) 1978-06-13 US disclosed
US-RE29669-E CYCLIZATION OF GLYCINEAMIDES PFIZER, INC. (US) 1978-06-13 US disclosed
US-4091032-A ANTIMICROBIAL AGENTS ABBOTT LABORATORIES (US) 1978-05-23 US disclosed
US-3971802-A ANTIINFLAMMATORY PFIZER INC. (US) 1976-07-27 US disclosed
US-3954786-A ANTIINFLAMMATORY AGENTS PFIZER INC. (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 ALDH1A1 2776/4885MAPT 2459/4885HPGD 3843/4885
US-20250368680-A1 METHOD FOR PRODUCING SALT OF AMINO ACID OR SALT OF PEPTIDE COMPOUND OR SOLVATE OF EITHER ONE OF SAID SALTS COMPRISING LITHIUM SALT PRECIPITATION STEP NPPA, DNPEP, NPEPPS ALDH1A1 4520/4885MAPT 584/4885HPGD 4724/4885
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME NEU1, NEU2, NEU4 ALDH1A1 474/4885MAPT 258/4885HPGD 1182/4885
US-12552796-B2 EED inhibitor, and preparation method therefor and use thereof HSD11B1, CYP4A11, CYP8B1 ALDH1A1 411/4885MAPT 970/4885HPGD 267/4885
US-20250313579-A1 LIGAND COMPOUNDS COMPRISING A CHELATING GROUP AS A BRIDGING GROUP SHBG, SLC40A1, TFRC ALDH1A1 3655/4885MAPT 3600/4885HPGD 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.