Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428734 | 0.90 | ALDH1A1 (0.39) | ALDH1A1POLBMAPK1DPP4HTT | |
| SCHEMBL8430829 | 0.89 | HTT (0.34) | HTT | |
| SCHEMBL8430464 | 0.84 | ALDH1A1 (0.36) | ALDH1A1DPP4HTTTGFBR1TRPV1 | |
| SCHEMBL8430883 | 0.78 | HTT (0.35) | HTT | |
| SCHEMBL8430850 | 0.78 | ALDH1A1 (0.38) | ALDH1A1POLBMAPK1TGFBR1 | |
| SCHEMBL8426870 | 0.77 | — | — | |
| SCHEMBL8429057 | 0.76 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL8427063 | 0.76 | MEN1 (0.34) | ALDH1A1POLBMAPK1DPP4HTT | |
| SCHEMBL8430913 | 0.74 | ALDH1A1 (0.38) | ALDH1A1POLBMAPK1HTT | |
| SCHEMBL8430920 | 0.73 | ALDH1A1 (0.35) | ALDH1A1POLBMAPK1HTTTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |