Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430920 | 0.89 | ALDH1A1 (0.35) | ALDH1A1HTTMAPTKDM4ETYMP | |
| SCHEMBL8427059 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TRPV1DPP4HTTTGFBR1 | |
| SCHEMBL8428900 | 0.84 | ALDH1A1 (0.39) | ALDH1A1HTTMAPTKDM4EGAA | |
| SCHEMBL8426961 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4ETGFBR1HPGD | |
| SCHEMBL8427033 | 0.78 | HTT (0.36) | HTTMAPT | |
| SCHEMBL8427094 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTGAAPKMHPGD | |
| SCHEMBL7213309 | 0.75 | KDM4E (0.40) | ALDH1A1DPP4HTTMAPTKDM4E | |
| SCHEMBL30610974 | 0.75 | KDM4E (0.40) | ALDH1A1DPP4HTTMAPTKDM4E | |
| SCHEMBL8428990 | 0.74 | ALDH1A1 (0.34) | ALDH1A1HTTMAPTKDM4ETGFBR1 | |
| SCHEMBL8428734 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TRPV1DPP4HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |