Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430679 | 0.88 | — | — | |
| SCHEMBL8428734 | 0.88 | ALDH1A1 (0.39) | ALDH1A1POLBMAPK1KDM4EMAPT | |
| SCHEMBL8430913 | 0.87 | ALDH1A1 (0.38) | ALDH1A1POLBMAPK1MAPTKMT2A | |
| SCHEMBL8426961 | 0.84 | ALDH1A1 (0.39) | ALDH1A1POLBMAPK1KDM4EMAPT | |
| SCHEMBL8426903 | 0.82 | — | — | |
| SCHEMBL8430943 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL8427059 | 0.78 | ALDH1A1 (0.36) | ALDH1A1POLBMAPK1TGFBR1 | |
| SCHEMBL8426833 | 0.77 | ALDH1A1 (0.36) | ALDH1A1POLBMAPK1MAPTKMT2A | |
| SCHEMBL10069606 | 0.75 | ALDH1A1 (0.37) | ALDH1A1POLBMAPK1MAPTKMT2A | |
| SCHEMBL10069629 | 0.73 | RGS4 (0.35) | ALDH1A1POLBMAPK1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |