Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428161 | 0.90 | CYP2C9 (0.51) | ALDH1A1LMNATSHRPOLBCYP2C9 | |
| SCHEMBL6948663 | 0.85 | POLB (0.52) | ALDH1A1SMN1; SMN2L3MBTL1LMNATSHR | |
| SCHEMBL8428070 | 0.83 | CA1 (0.54) | ALDH1A1SMN1; SMN2LMNATSHRPOLB | |
| SCHEMBL9025227 | 0.82 | ALDH1A1 (0.46) | MAPK1ALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL8428126 | 0.82 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2L3MBTL1LMNATSHR | |
| SCHEMBL8423248 | 0.81 | APP (0.43) | ALDH1A1SMN1; SMN2LMNATSHRHPGD | |
| SCHEMBL8427533 | 0.79 | MAPT (0.65) | ALDH1A1SMN1; SMN2L3MBTL1LMNATSHR | |
| SCHEMBL8425552 | 0.78 | POLB (0.55) | ALDH1A1SMN1; SMN2L3MBTL1LMNATSHR | |
| SCHEMBL6948645 | 0.73 | KMT2A (0.54) | ALDH1A1SMN1; SMN2LMNATSHRPOLB | |
| SCHEMBL17114436 | 0.72 | MAPK1 (0.65) | MAPK1ALDH1A1SMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |